Computer Science, Morphogenesis and Variability From developing code to decoding development

Projects

We develop open-source tools for image registration, spatial transcriptomics, organoid analysis, and cell lineage handling. All software is freely available on GitHub.

Tapenade
Tapenade 3D organoid image analysis

A fully-visual pipeline for quantitative analysis of 3D organoid images from deep imaging microscopy.

sc3D
sc3D 3D spatial transcriptomics

A library for manipulating and analyzing 3D spatial transcriptomics data at near single-cell resolution.

registration-tools
registration-tools 3D movie registration

A library to register 3D movies in space and/or time, enabling alignment of live-imaging datasets.

napari-sc3D-viewer
napari-sc3D-viewer napari plugin

A napari viewer designed for interactive exploration of 3D spatial transcriptomics data.

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napari-3D-registration
napari-3D-registration napari plugin

A napari plugin providing a graphical interface for the registration-tools library.

LineageTree
LineageTree Cell lineage handling

A library to handle, manipulate, and analyse cell lineage trees from time-lapse imaging.

ASTEC
ASTEC Cell detection & tracking

Automated cell detection and tracking algorithm for whole-embryo light-sheet imaging data.

napari-obj
napari-obj napari plugin

A napari plugin for loading and displaying .obj 3D mesh files.

SVF
SVF Statistical Vector Flow

A computational library implementing Statistical Vector Flow for morphological atlas construction.

Mouse-Atlas
Mouse-Atlas Mouse embryo tracking

Standalone implementation of the tracking code from McDole et al. 2018 (Cell).

Cell-cell interaction model
Cell-cell interaction model Signaling simulation

Computational model simulating cell-cell signaling interactions during embryogenesis.

CenTuri Course
CenTuri Course Python via Turing models

Educational resource teaching Python programming through Turing-model simulations of biological patterns.